Table 1.
Recovered worms and their percent reduction in mice treated by artemisinin derivatives.
| Compound | Structure | Recovered worms and percent reduction |
||
|---|---|---|---|---|
| Total | Male | Female | ||
| Control | – | 44.0 | 23.9 | 20.1 |
| Artemiside |  |
4.6 89.5% |
2.6 94.1% |
2.0 95.5% |
| Artemisone |  |
3.0 93.2% |
2.0 95.5% |
1.0 97.7% |
| CKW03 |  |
9.2 79.1% |
5.4 87.5% |
3.8 91.4% |
| Artemether |  |
5.4 87.7% |
3.2 92.7% |
2.2 95.0% |
Infected mice were treated at day 21 post infection (PI) by gavage. The mice were dissected at day 49 PI and schistosomes counted. n = 5 in experimental groups and 10 in the control group. P < 0.01 in all experimental groups.