Table 2.
Day of treatment PI |
Artemisone in gel/mouse |
Control count |
Experimental count |
Percent inhibition |
---|---|---|---|---|
7, 14a | 4 mg | 18.6 | 5.0 | 73.1* |
21, 28 | 4 mg | 40.2 | 8.5 | 81.6* |
21, 28, 35 | 4 mg | 39.5 | 1.6 | 95.9* |
21 | 4 mg | 40.2 | 24.2 | 39.8 |
34 | 4 mg | 61.4 | 11.0 | 82.1* |
42, 49 |
4 mg |
30.2 |
2.3 |
92.4* |
Praziquantel in gel/mouse |
||||
7, 14a | 4 mg | 30.2 | 25.0 | 17.3 |
42, 49 | 4 mg | 30.2 | 0.2 | 99.3* |
Infected mice were treated at various days PI. Mice were dissected on day 49–51 PI and schistosomes counted. n = 5 in all groups. *Significant vs. control (p < 0.01).
Artemisone is significant vs. praziquantel.