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. 2017 May 4;7(2):241–247. doi: 10.1016/j.ijpddr.2017.05.002

Table 2.

Recovered worms and percent reduction in mice treated by artemisone and praziquantel administered in gel

Day of
treatment PI
Artemisone in
gel/mouse
Control
count
Experimental
count
Percent inhibition
7, 14a 4 mg 18.6 5.0 73.1*
21, 28 4 mg 40.2 8.5 81.6*
21, 28, 35 4 mg 39.5 1.6 95.9*
21 4 mg 40.2 24.2 39.8
34 4 mg 61.4 11.0 82.1*
42, 49
4 mg
30.2
2.3
92.4*

Praziquantel in
gel/mouse



7, 14a 4 mg 30.2 25.0 17.3
42, 49 4 mg 30.2 0.2 99.3*

Infected mice were treated at various days PI. Mice were dissected on day 49–51 PI and schistosomes counted. n = 5 in all groups. *Significant vs. control (p < 0.01).

a

Artemisone is significant vs. praziquantel.