. 2017 May 4;7(2):241–247. doi: 10.1016/j.ijpddr.2017.05.002

Table 3.

Percent inhibition of Plasmodium falciparum development by artemisone released in vitro from gels.

Day of gel in media	Supernatant dilution
Day of gel in media	1/3125	1/15,625	1/78,125
3	95%^a	68%^a	17%
7	94%^a	14%	11%

Considerable amounts of active artemisone were released in vitro, spanning at least 7 days. For example, a final dilution of 1/15,625 of supernatant collected on day 3 inhibited 68% of parasite development (meaning that the amount of artemisone that was released in days 3 and 5 was about 16 and 5 μg, respectively).

The ED50 of free artemisone was estimated by identical methods and was about one ng/ml.

Significant in comparison with supernatants of blank gels.