Table 1.
Clusters of functionally-related genes characterised in the childhood-onset asthma module using DAVID13, 41.
| Gene cluster | Functional annotation | Number of genes | List of genes in a cluster |
|---|---|---|---|
| 1 | Immune response | 22 | BAI3, BTN3A3, CCBP2, CCR8, CCR9, CCRL1, CD48, CMKLR1, CXCR5, IL18R1, IL18RAP, IL1RL1, IL1RL2, KLRC4, LPHN3, MICB, NCR3LG1, RAET1E, RAET1G, SIRPD, ULBP1, ULBP3 |
| 2 | Chemokines/Chemotaxis | 15 | CCBP2, CCL1, CCL13, CCL16, CCL19, CCL25, CCL27, CCL4, CCL8, CCR8, CCR9, CCRL1, CMKLR1, CXCL13, CXCR5 |
| 3 | Cadherins/Cell-adhesion | 8 | DCHS1, FREM2, ITGAX, PCDH20, PCDH21, PCDHGA11, RAET1E, RAET1G |
| 4 | Zinc finger proteins/Transcription regulation | 8 | IKZF3, ZNF165, ZNF174, ZNF192, ZNF20, ZNF24, ZNF434, ZNHIT3 |