Fig. 3.

VSMC PDI externalization was unaltered by cytoskeletal disorganization or lysosome impairment. (A) Immunofluorescence staining of PDI (red) and phalloidin, showing F-actin (white) in permeabilized VSMC at baseline or after incubation with CytD 0.5 μM and Methylamine 10 mM for 1.5 h. (B) Immunofluorescence staining of PDI (red) in non-permeabilized VSMC in basal condition or after treatment as in (A). All images shown are representative of at least three independent experiments. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)