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. 2017 Apr 26;7:1184. doi: 10.1038/s41598-017-01338-7

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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mRNA expression profiles in spleen tissue and CIK cells. Transcripts of 6 genes with more than one genotype in 9 genes with confirmed SNPs were quantified in resistant and susceptible groups in spleen (A) and CIK (B) by qRT-PCR (n = 3). 18 S rRNA and EF1α as reference genes were used in individuals and cells respectively. Fold changes of mRNA expressions were relative to corresponding susceptible samples (defined as 1). *P < 0.05; **P < 0.01; ***P < 0.001; ‘NS’, not significant, P > 0.05. The normalized absolute quantification FPKM values of corresponding genes in RNA-Seq datasets of spleen and CIK were demonstrated in (C) and (D), respectively.