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. 2017 Apr 26;7:1172. doi: 10.1038/s41598-017-01178-5

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Relationship between peripheral blood expression levels of AKAP7 splice variants and ITGA3. (A–H) Relationship between transcriptional expression levels of AKAP7 splice variants and total transcriptional expression levels of ITGA3 in the peripheral whole blood of validation cohort AIS patients at emergency department admission as measured using qRT-PCR. Splice variants which are translated to produce PKA-binding AKAP7 isoforms are highlighted. Expression levels are presented as log₂ fold differences relative to the sample of lowest expression.