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. 2017 May 15;7:181. doi: 10.3389/fcimb.2017.00181

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Copyright © 2017 Liu, Wang, Qin, Cheng, Yeo, He, Ma, Liu, Li and Bae.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Catheter colonization and dissemination of NM and clpP mutant strains in a mouse device-related infection model. Implanted catheter segments were injected with 1 × 10⁸ bacteria and mice were sacrificed after 7 days. Colony forming units (CFU) per catheter (A), per g peri-catheter tissue (B), per ml blood (C), per g liver (D), per g spleen (E), per g kidney (F) recovered from animals infected with wild type (NM) and clpP mutant strain. Statistical significance (p-values) is indicated in the figure.