Effects of antiretroviral therapy (ART) initiation and depressive symptoms on cumulative mortality in the Women's Interagency HIV Study, United States, 1998–2011. Women who had not initiated ART are represented by the solid line and women who had initiated ART by the dashed line (A). Women experiencing depressive symptoms are represented by the solid line and women not experiencing depressive symptoms by the dashed line (B). Weighted models adjusted for age at enrollment, race, CD4 cell count, log10 HIV RNA, baseline CD4 cell count, and baseline log10 HIV RNA. Weights for depressive symptoms also adjusted for depressive symptoms at the previous visit.