Figure 2.

Nrf2 and CYP2A5 protein expressions in HFD feeding mice. Nrf2 protein expression in mouse hepatocytes nucleus and its quantity relative to Histon H1 is shown in panel (A). Nrf2 protein expression in liver cytoplasm and its quantity relative to β-actin is shown in panel (B). Hepatic CYP2A5 protein expression in WT and Nrf2-null mice, which fed with CD and HFD, is revealed in panel (C) and the quantity relative to β-actin is shown in panel (D). ^* represent statistical difference caused by HFD within WT or Nrf2-null groups; $ represent statistical difference caused by Nrf2 deficiency on the same diet. ^* 0.01 < P < 0.05, ^**P < 0.01; $ 0.01 < P < 0.05, $$P < 0.01.