Table 1.
List of Aminopeptidase N inhibitor peptides.
| Peptide | IC50 (µM) | Peptide | Ki (µM) |
|---|---|---|---|
| Bestatin | 3.7 ± 0.4 | cyc-LHSPW | 24.7 ± 1.4 |
| nHSPW | 6.5 ± 0.5 | cyc-LHSP | 121.4 ± 21.4 |
| AHSPW | 9.4 ± 1.1 | cyc-LHS | >500 |
| LHSPW | 10.6 ± 1.2 | cyc-PHSPW | >500 |
| HSPW | 43.3 ± 3.9 | cyc-AHSPW | >500 |
| PHSPW | 82.5 ± 9.3 | cyc-nHSPW | >500 |
| EHSPW | 115.4 ± 17.2 | ||
| nDQIY | >500 | For-HSPW | >500 |
| LDSTF | >500 | Suc-HSPW | >500 |
| DSTF | >500 | Cbz-HSPW | >500 |
| ADARK | >500 | Ac-HSPW | >500 |
| DARK | >500 | For-LHSPW | >500 |
| INDFL | >500 | Suc-LHSPW | >500 |
| AHLFN | >500 | Cbz-LHSPW | >500 |
| FSLSK | >500 | Ac-LHSPW | >500 |
| SKSGQ | >500 | ||
| AHSTF | >500 | cyc-LDSTF | >500 |
| FYLRE | >500 | cyc-ADARK | >500 |
| FDWWG | >500 | ||
| RDLVD | >500 | ||
| EPKVA | >500 |