Table 2.
Mean T2* values of six brain region in PD patients analysed at 0, 3 and 6 months after administration of either 20 mg/kg/day or 30 mg/kg/day deferiprone or receiving placebo.
| Months | Substantia Nigra | Red Nucleus | Dentate | Caudate | Putamen | Pallidum | |
|---|---|---|---|---|---|---|---|
| Placebo | 0 | 28.09 ± 1.52 | 27.37 ± 0.82 | 30.51 ± 0.59 | 43.92 ± 1.22 | 37.26 ± 1.18 | 27.41 ± 1.39 |
| 3 | 29.36 ± 1.84 | 28.76 ± 1.06 | 30.54 ± 0.86 | 43.65 ± 1.62 | 35.76 ± 0.90 | 26.25 ± 0.58 | |
| 6 | 28.22 ± 1.81 | 28.58 ± 1.23 | 30.74 ± 0.65 | 45.98 ± 2.08 | 36.55 ± 0.86 | 26.43 ± 0.87 | |
| 20 mg/kg/day | 0 | 26.41 ± 1.25 | 28.10 ± 1.19 | 29.14 ± 0.84 | 38.86 ± 1.53 | 33.99 ± 1.80 | 25.55 ± 1.23 |
| 3 | 27.05 ± 1.23 | 26.86 ± 1.56 | 30.15 ± 0.49 | 40.29 ± 1.74 (**) | 33.54 ± 1.27 | 25.43 ± 1.08 | |
| 6 | 27.68 ± 1.06 | 27.78 ± 1.05 | 30.59 ± 0.87 (**) | 41.05 ± 3.43 (**) | 33.94 ± 1.75 | 25.89 ± 0.96 | |
| 30 mg/kg/day | 0 | 23.89 ± 2.24 | 27.21 ± 1.56 | 27.16 ± 1.56 | 40.75 ± 1.68 | 33.67 ± 2.14 | 25.72 ± 1.76 |
| 3 | 23.74 ± 1.84 | 26.99 ± 1.04 | 29.04 ± 1.82 | 44.69 ± 1.93 (**) | 37.24 ± 2.31 | 24.97 ± 1.14 | |
| 6 | 24.57 ± 1.69 | 27.55 ± 1.12 | 29.86 ± 1.10 (**) | 44.55 ± 1.57 (**) | 38.19 ± 2.04 | 26.26 ± 1.33 |
Results are presented as mean ± standard error. **p < 0.01.