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. 2017 May 3;7:1376. doi: 10.1038/s41598-017-01299-x

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effect of injury severity on tissue sparing 12 weeks after spinal cord injury. Spared tissue was measured using Eriochrome Cyanine stained sections from 13.6 mm rostral and 13.6 mm caudal to the site of injury. (A) The total spared tissue in percent, relative to the entire area of the spinal cord of the same section was calculated for the 40 (red), 20 (blue), 10 cm (green), and SHAM (black) groups. (B) The total amount of tissue sparing (cumulative percent) was calculated using the area under the curve of total spared tissue (%) for the 40 (red), 20 (blue), 10 cm (green), and SHAM (black) groups. Asterisks indicate sparing for which significant differences were found between groups with ANOVA. Data is presented as means ± SEM for n = 4 animals per group. SCI, spinal cord injury.