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. 2017 May 3;7:1376. doi: 10.1038/s41598-017-01299-x

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effect of Injury Severity on total Systemic miRNA. (A) The total number of normalized miRNA counts in the 40 cm (red), 20 cm (blue), 10 cm (green), and SHAM (black) groups. Data points represent the average of the normalized total miRNA reads for n = 4 animals per group and time point (see Table 1). (B) The cumulative miRNA expression over time in the 40 cm (red), 20 cm (blue), 10 cm (green), and SHAM (black) groups. Asterisks indicate significant differences determined by ANOVA. Data is presented as means ± SEM.