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. 2017 May 3;7:1467. doi: 10.1038/s41598-017-01561-2

Figure 5.

Figure 5

KXS series formulae regulate mRNA expressions of proteins relating to metabolic pathway of neurotrophic factors in hippocampus of CUMS-treated mice. (A) The treatment of KXS series formulae and fluoxetine in the mice were same as that in Fig. 1. The hippocampus tissues were collected after one-week treatment and mRNA expression levels of proteins relating to synthesis of neurotrophic factors were analyzed. (B) Drug treatment and sample preparations were same as (A) and mRNA expression levels of proteins relating to degradation of neurotrophic factors were analyzed. Comparisons between groups were carried out by a one-way ANOVA followed by a post-hoc Bonferroni test. Values are expressed in the percentage of non-stressed group as Mean ± SEM (n = 8). #p < 0.05, ##p < 0.01 (compared with non-stressed group); *p < 0.05, **p < 0.01 (compared with stressed group).