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Sanguinarine induced GC cycle arrest and cell apoptosis. (A) Cell cycle analysis showed that sanguinarine increased GC cell proportion in cell cycle S phase in a dose‐dependent manner. P < 0.05. (B) Cell apoptotic analysis indicated that sanguinarine induced cell apoptosis in a dose‐dependent manner. **P < 0.01. (C) Expression of DUSP4 in GC cells treated by sanguinarine of different concentrations.
