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. 2017 May 3;7:1446. doi: 10.1038/s41598-017-01556-z

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Comparison of SSGA, MSGA and Triple-Link Algorithm with the cumulative Davies-Bouldin (DB) indices. The cumulative DB indices of top i subnetworks derived from SSGA, MSGA and Triple-Link Algorithm where i = (2, …, 29, 30). (A) The distances used for calculating DB were based on Spearman’s rank correlation; (B). The distances used for calculating DB were based on Pearson correlation; (C). The distances used for calculating DB were based on Kendall’s rank correlation; (D). The distances used for calculating DB were based on Weighted Rank correlation. In all cases, a higher DB index of top i subnetworks reflects a more tightly averaged coordination of the top i subnetworks.