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. 2017 May 3;7:1481. doi: 10.1038/s41598-017-01515-8

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Overexpression of Foxp3 attenuates plasma mouse anti-sheep IgG antibody production but does not affect immune complex deposition in inflamed glomeruli. (A) Representative immunofluorescence staining of glomeruli from WT and Tg mice with anti-GBM GN for the deposition of sheep IgG (a and b), mouse IgG (c and d) and mouse C3 (e and f). (B) ELISA test of plasma mouse anti-sheep IgG from WT and Tg mice with anti-GBM GN. Each bar represents mean ± SEM. ^### p < 0.001 compared with the WT mice. n = 6–8 mice per group.