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. 2017 May 3;7:1392. doi: 10.1038/s41598-017-01476-y

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Measured dynamic elastic moduli of collagen fibrils for different loading rates (1–100 Hz). (a) Elastic moduli versus Col-III:Col-I mixing ratio expressed as the mean ± standard error. The differences were found to be statistically significant (p < 0.05); (b) The semi-logarithmic diagrams of the average elastic moduli versus Col-III:Col-I mixing ratios and the fitted curves. F1, F2, and F3 denote the logarithmic function of the elastic modulus E at 1, 10, and 100 Hz, respectively. The elastic moduli obtained at 100 Hz were found to be greater than the ones obtained at 10 Hz. Similarly, the moduli obtained at 10 Hz were greater than the ones obtained at 1 Hz.