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. 2017 May 3;7:1472. doi: 10.1038/s41598-017-01650-2

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The Contrast-enhanced ultrasound (CEUS) images of different papillary thyroid carcinoma (PTC) patients with extracapsular extension (ECE). (a) CEUS image of a 48-year-old male PTC patient with ECE. The CEUS image clearly showed that the anterior thyroid capsular was invaded by PTC (arrow). (b) CEUS image of a 58-year-old female PTC patient with ECE. The nodule showed by arrow head was the PTC nodule. ECE was not clearly confirmed by CEUS (arrow). (c) CEUS image of a 50-year-old female PTC patient with ECE. The nodule showed by arrow head was the PTC nodule. ECE was not clearly detected by CEUS (arrow).