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. 2017 May 3;7:1472. doi: 10.1038/s41598-017-01650-2

Table 2.

Comparison of CEUS qualitative and quantitative parameters between ECE and non-ECE group.

Parameters Characteristics ECE P value
Yes (n = 57) No (n = 52)
The degree of contrast agent distribution Diffuse heterogeneous enhancement 28 22
Diffuse homogeneous enhancement 9 10 0.762
Dotted enhancement 20 20
Border type Well-defined border 23 23 0.682
Ill-defined border 34 29
Enhancement degree Hypoenhancement 47 42
Isoenhancement 9 9 0.975
Hyperenhancement 1 1
RT(sec) 6.86 ± 5.33 9.92 ± 8.51 0.025
TTP(sec) 23.07 ± 8.42 27.67 ± 11.07 0.016
PI(dB) 7.67 ± 2.14 7.89 ± 2.16 0.593
WIS(dB/sec) 1.27 ± 0.59 0.91 ± 0.61 0.003
TPH(sec) 51.72 ± 15.33 76.85 ± 24.55 0.000
AUC(dBsec) 541.35 ± 200.87 675.16 ± 196.58 0.001

CEUS: contrast-enhanced ultrasound. ECE: extracapsular extension. RT: rise time. TTP: time to peak. PI: peak intensity. WIS: wash in slope. TPH: time from peak to one half. AUC: area under the curve.