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. 2017 Mar 16;13(5):3662–3668. doi: 10.3892/ol.2017.5865

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Figure 4. — Lico-E-induced apoptosis is mediated by the death receptor-dependent extrinsic and mitochondrial-dependent intrinsic apoptotic signaling pathways in FaDu cells. (A) Western blotting of FasL and caspase-8. (B) Western blotting of Bcl-2, Bcl-xL, p53, Bax, Bad and Apaf-1. (C) Western blotting of caspase-3 and PARP. Lico-E, licochalcone-E; FasL, Fas ligand; Bcl-2, apoptosis regulator Bcl-2; Bcl-xL, Bcl-2-like protein 1; Bax, apoptosis regulator BAX; Bad, Bcl-2-associated agonist of cell death; Apaf-1, apoptotic protease-activating factor 1; PARP, poly (ADP-ribose) polymerase.