Table IV.
Binomial logistic regression analysis in patients with pituitary adenoma and the control group.
| Gene | Model | Genotype | OR (95% CI) | P-value | AIC |
|---|---|---|---|---|---|
| SIRT1 rs12778366 | Co-dominant | T/T | 1.000 | 720.516 | |
| T/C | 0 (0.000) | 0.995 | |||
| C/C | 7.530 (4.087–13.087) | <0.001 | |||
| Recessive | T/T+T/C | 1.000 | 780.895 | ||
| C/C | 9.171 (4.982–16.982) | <0.001 | |||
| Additive | – | 1.584 (1.187–2.187) | 0.002 | 780.214 | |
| STAT3 rs744166 | Co-dominant | A/A | 1.000 | 801.223 | |
| G/G | 0.879 (0.603–1.603) | 0.504 | |||
| G/G | 0.396 (0.211–0.211) | 0.004 | |||
| Recessive | A/A+G/A | 1.000 | 799.670 | ||
| G/G | 0.425 (0.234–0.234) | 0.005 | |||
| Additive | – | 0.702 (0.541–0.541) | 0.008 | 801.881 |
OR, odds ratio; CI, confidence interval; AIC, Akaike Information Criterion; SIRT1, sirtuin 1; STAT3, signal transducer and activator of transcription 3.