Table I.
Renal disease in syndromic MIDs and nsMIDs.
| MID | RF | NL | NS | RC | RTA | BLS | THFS | FSGS | TIN | NC |
|---|---|---|---|---|---|---|---|---|---|---|
| MELAS | Yes | N | N | N | N | N | N | Yes | N | N |
| KSS | Yes | N | N | N | Yes | Yes | Yes | N | N | Yes |
| MDS | N | N | N | N | Yes | N | N | N | N | Yes |
| LS | N | N | N | Yes | Yes | N | N | N | Yes | N |
| CPEO | Yes | N | N | N | N | N | N | N | N | N |
| PS | N | N | N | Yes | Yes | N | N | N | N | N |
| LHON | N | N | N | N | N | N | N | N | Yes | N |
| PCQD | N | N | Yes | N | N | N | N | Yes | N | N |
| XLSA | Yes | N | N | N | N | N | N | N | N | N |
| GRACILE | N | N | N | N | N | N | Yes | N | N | N |
| MEGDEL | Yes | N | N | N | N | N | N | N | N | N |
| HUPRA | Yes | N | N | N | N | N | N | N | N | N |
| MLASA | N | N | N | N | Yes | N | N | N | N | N |
| MSL | N | N | N | N | Yes | N | N | N | N | N |
| PDHD | N | N | N | N | Yes | N | N | N | N | N |
| nsMIMODS | Yes | Yes | Yes | Yes | Yes | N | N | Yes | Yes | Yes |
RF, renal failure; NL, nephrolithiasis; NS, nephrotic syndrome; RC, renal cysts; RTA, renal tubular acidosis; BLS, Bartter-like syndrome; TDFS, Toni-Debré-Fanconi syndrome; FSGS, focal segmental glomerulosclerosis; TIN, tubulo-interstitial nephritis (nephrophthisis); NC, nephrocalcinosis; LS, Leigh syndrome; PCQD, primary coenzyme-Q deficiency; XLSA, X-linked sideroblastic anemia; nsMIMODS, non-specific MIMODS; N, not reported.