Table I.
Clinicopathological characteristics of patients.
| Extent of PLND | |||||
|---|---|---|---|---|---|
| Expanded | |||||
| Characteristic | Standarda,n (%) | Expandedb,n (%) | P-value | Extended(standard + external iliac) | More extended(standard + external and common iliac) |
| Total no. of patients | 301 (64.5) | 166 (35.5) | 125 | 41 | |
| Age, years | |||||
| <70 | 210 (69.8) | 112 (67.5) | 0.6082 | 90 (72.0) | 22 (53.7) |
| ≥70 | 91 (30.2) | 54 (32.5) | 35 (28.0) | 19 (46.3) | |
| Preoperative PSA, ng/ml | |||||
| ≤10 | 222 (73.8) | 111 (66.9) | 0.1157 | 84 (67.2) | 27 (65.9) |
| >10 | 79 (26.2) | 55 (33.1) | 41 (32.8) | 14 (34.1) | |
| Clinical T stage | |||||
| cT1c | 195 (64.8) | 121 (72.9) | 0.0708 | 92 (73.6) | 29 (70.7) |
| ≥cT2a | 106 (35.2) | 45 (27.1) | 33 (26.4) | 12 (29.3) | |
| Biopsy Gleason score | |||||
| ≤7 | 222 (73.8) | 131 (78.9) | 0.2146 | 98 (78.4) | 33 (80.5) |
| >8 | 79 (26.2) | 35 (21.1) | 27 (21.6) | 8 (19.5) | |
| Pathological T stage | |||||
| ≤pT2 | 186 (61.8) | 107 (64.5) | 0.5682 | 77 (61.6) | 30 (73.2) |
| ≥pT3 | 115 (38.2) | 59 (35.5) | 48 (38.4) | 11 (26.8) | |
| Final Gleason score | |||||
| ≤7 | 239 (79.4) | 125 (72.3) | 0.3068 | 95 (76.0) | 30 (73.2) |
| >8 | 62 (20.6) | 41 (27.7) | 30 (24.0) | 11 (26.8) | |
| Extraprostatic extension | |||||
| Negative | 208 (69.1) | 116 (69.9) | 0.8622 | 86 (68.8) | 30 (73.2) |
| Positive | 93 (30.9) | 50 (30.1) | 39 (31.2) | 11 (26.8) | |
| Resection margin | |||||
| Negative | 239 (79.4) | 140 (84.3) | 0.1868 | 103 (82.4) | 37 (90.2) |
| Positive | 62 (20.6) | 26 (15.7) | 22 (17.6) | 4 (9.8) | |
| Seminal vesicle invasion | |||||
| Negative | 281 (93.4) | 159 (95.8) | 0.2707 | 118 (94.4) | 41 (100) |
| Positive | 20 (6.6) | 7 (4.2) | 7 (5.6) | 0 | |
| Lymph node metastasis | |||||
| Negative | 294 (97.7) | 160 (96.4) | 0.4257 | 120 (96.0) | 40 (97.6) |
| Positive | 7 (2.3) | 6 (3.6) | 5 (4.0) | 1 (2.4) | |
| PSA recurrence | 46 (15.3) | 22 (13.3) | 0.5526 | 18 (14.4) | 4 (9.8) |
a
Standard indicates dissection of the obturator + internal iliac nodes.
b
Expanded includes the extended (standard + external iliac) and more extended (standard + external and common iliac) groups. Clinical and pathological staging was based on the 2009 Tumor-Node-Metastasis classification. P-values calculated using χ2 test. PLND, pelvic lymph node dissection; PSA, prostate-specific antigen.