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. 2017 Mar 7;13(5):3057–3065. doi: 10.3892/ol.2017.5818

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Comparison of protein expression in osteosarcoma and adjacent noncancerous bone tissues. Representative in situ hybridization images for miR-335 expression in (A) osteosarcoma tissues and (B) adjacent noncancerous bone tissues (original magnification, ×400). Compared with the adjacent noncancerous bone tissues, the expression of (C) Rock1 protein was significantly increased, while (D) miR-335 was significantly decreased in osteosarcoma tissues. miR, microRNA; Rock1, Rho-associated serine-threonine protein kinase 1.