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Western blot analysis revealed that siRNA-mediated RKIP silencing blocked IL-6-induced STAT3 phosphorylation in (A) A549 cells and (B) NCI-H1299 cells. RKIP, Raf kinase inhibitor protein; IL-6, interleukin 6; STAT3, signal transducer and activator of transcription; pSTAT3, phosphorylated signal transducer and activator of transcription 3; siRNA, small interfering RNA.
