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Immunohistochemical staining of HLA-E among the four groups at a magnification of ×400. (A) Negative expression of HLA-E in normal colorectal mucosa. (B) Negative expression of HLA-E in colorectal adenoma. (C) Weak positive expression of HLA-E in early colorectal cancer. (D) Strong positive expression of HLA-E in advanced colorectal cancer. HLA-E, human leukocyte antigen class I histocompatibility antigen, alpha chain E.
