Table 2.
The levels of 5-HT, iron and metabolism-related proteins in CSF among control, non-fatigue and fatigue groups.
| Control group (29 cases) | Non-fatigue group(59 cases) | Fatigue group(63 cases) | P1 | P2 | P3 | |
|---|---|---|---|---|---|---|
| Neurotransmitters | ||||||
| 5-HT [ng/mL, median (quartile)] | 10.617 (5.732~115.828) | 8.934 (4.421~107.512) | 5.546 (4.312~338.01) | 0.094 | 0.000** | 0.000** |
| Iron and metabolism-related proteins | ||||||
| Iron [nmol/mL, median (quartile)] | 0.380 (0.263~0.612) | 0.411 (0.261~0.8254) | 0.632 (0.321~0.845) | 0.354 | 0.000** | 0.004** |
| Transferrin [ug/ml, median (quartile)] | 0.079 (0.062~0.083) | 0.104 (0.084~0.123) | 0.192 (0.073~0.214) | 0.001** | 0.000** | 0.003** |
| Lactoferrin (ug/ml, mean ± SD) | 148.471 ± 65.153 | 138.822 ± 61.371 | 134.295 ± 53.764 | 0.231 | 0.114 | 0.614 |
| Ferritin [ng/ml, median (quartile)] | 5.291 (2.592~20.723) | 5.771 (3.043~14.221) | 5.854 (3.632~17.231) | 0.783 | 0.63 | 0.853 |
5-HT = serotonin; P1: non-fatigue group vs. control group; P2: fatigue group vs. control group, P3: non-fatigue group vs. fatigue group. **P < 0.01.