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. 2016 Dec 21;6:18. doi: 10.1038/s41598-016-0025-0

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© The Author(s) 2016

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Overview of GSEA results. Effects of rpoB(R) over-expression and pH increase are reported by contrasting the rpoB(R) strain to wild type strain data. Gene-sets with Normalized Enrichment Score (NES) >1.70 and False Discovery Rate (FDR) <0.1 in at least one of the contrasts are reported. Green and red colors indicate, respectively, up-regulation and down-regulation in test strain vs. reference strain. If a set passed these thresholds in a contrast, the background of the cell is colored in pale green. For each set in each contrast, the width of the rectangle represents the mean log₂FC of the leading edge subset, while the height represents the NES. Gene-sets are labeled with an ID indicating whether they consist in clustered (ID number preceded by the letter C) or dispersed (ID number preceded by the letter D) genes. Abbreviations: wt, wild type strain; BR, rpoB(R) strain.