Table II.
Univariate and multivariate analysis of overall survival in 110 ESCC patients.
| Univariate analysis | Multivariate analysis | ||
|---|---|---|---|
| Variables | P-value | Hazard ratio (95% CI) | P-value |
| Age, years | 0.726 | 0.897 | |
| ≤60 | 1 | ||
| >60 | 0.967 (0.580–1.580) | ||
| Gender | 0.413 | 0.287 | |
| Male | 1 | ||
| Female | 0.727 (0.353–1.353) | ||
| Location | 0.903 | ||
| Ut | 0.901 | 1 | |
| Mt | 0.918 | 1.065 (0.583–1.583) | 0.838 |
| Lt | 0.704 | 1.059 (0.579–1.579) | 0.853 |
| Pathological grade | 0.012 | 0.001 | |
| Well-differeniated | 1 | ||
| Moderately/poorly-differentiated | 2.594 (1.516–4.516) | ||
| Lymph node metastasis | <0.001 | 0.001 | |
| Negative | 1 | ||
| Positive Clinical | 2.863 (1.574–5.574) | ||
| Clinical stage | <0.001 | <0.001 | |
| IA-IIB | 1 | ||
| IIIA-IV | 3.710 (1.994–6.994) | ||
| CMTM3 expression | 0.012 | 0.036 | |
| High | 1 | ||
| Low | 1.961 (1.046–3.046) | ||
CMTM3, human chemokine-like factor-like MARVEL transmembrane domain-containing 3; ESCC, esophageal squamous cell carcinoma; Ut, upper thoracic; Mt, middle thoracic; Lt, lower thoracic; CI, confidence interval.