Figure 2.

Human primary osteoblast-like cells were cultured with different concentrations of AMP and gentamicin for three days. Viability (A) and alkaline phosphatase (AP) activity (B) were determined. Values for AP were normalized to 10⁴ cells and compared to control (untreated cells, 100%). Results are means of n = 6, cells from two donors, triplicates.). Data are shown as means with standard deviation. Kruskal-Wallis, Mann-Whitney, Bonferroni-Holm post-hoc test. Significant inhibition compared to the control group, viability: AMP1 ≥ 100 µg/ml, AMP2 ≥ 267 µg/ml, AMP3 ≥ 68 µg/ml, AMP4 ≥ 251 µg/ml, AMP5 ≥ 63 µg/ml; Alkaline phosphatase activity: AMP1 all concentrations, AMP2–4 ≥ 125 µg/ml, AMP5 ≥ 63 µg/ml.