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. 2017 May 4;7:1504. doi: 10.1038/s41598-017-01613-7

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The global view of C-Tc network for Semen Strychni and Myristica Semena which is soly related to the CNS diseases. The net is composed of 11 bioactive compounds (cyan squares) from Myristica Semena and 12 ones from Stigma Croci (orange squares), as well as 78 potential protein targets (circles) these compounds interact with. The pink circles (53) are the common targets of both herbs. Node size is proportional to its degree.