Correlation between colorectal tumor tissue and corresponding NAT for (A) C3M and (B) VICM in supernatant collected after 24 h of ex vivo culture. Indicated are the Pearson's correlation coefficient (r), the goodness of fit (R2) and the P-value. MMP, matrix metalloprotease; C3M, MMP-degraded type III collagen; VICM, citrullinated and MMP-degraded vimentin; NAT, non-neoplastic adjacent tissue.