Table V.
Correlation of clinical features of LBC samples with miR-205 expression levels.
| Characteristics | All cases | High miR-205 (>median) | Low miR-205 (<median) | P-valuea |
|---|---|---|---|---|
| Age (n=140) | ||||
| <32.5 | 70 | 39 | 31 | 0.1763 |
| >32.5 | 70 | 31 | 39 | |
| HPV (n=115) | ||||
| Positive | 93 | 47 | 46 | 0.7352 |
| Negative | 22 | 12 | 10 | |
| HPV subtypes (n=90) | ||||
| HPV16, HPV18 | 43 | 23 | 20 | 0.5267 |
| Non HPV16, non HPV18 | 47 | 22 | 25 | |
| Cytology (n=140) | ||||
| LSIL | 45 | 20 | 25 | 0.3093 |
| HSIL | 74 | 40 | 34 | |
| Histology (n=123) | ||||
| CIN1 | 35 | 17 | 18 | 0.8391 |
| CIN2+ | 79 | 40 | 39 | |
| Final diagnosis (n=140) | ||||
| CIN1 | 29 | 11 | 18 | 0.1657 |
| CIN2+ | 95 | 50 | 45 |
a
Two-tailed χ2 test (without Yates correlation). High or low miR-205 expression based on the median expression level. LBC, liquid-based cytology; HPV, human papillomavirus; LSIL, low-grade squamous intraepithelial lesion; HSIL, high-grade squamous intraepithelial lesion; CIN1, cervical intra-epithelial neoplasia grade 1; CIN2+, cervical intra-epithelial neoplasia grade 2 or worse.