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. 2017 May 4;7:1494. doi: 10.1038/s41598-017-01652-0

Table 2.

Correlations between NLR, PLR and PC and main clinicopathological variables for the 603 patients under study.

No. of patients H-NLR H-PLR H-PC
Age p = 0.026 p = 0.747 p = 0.398
 ≤68.9 years 299 66 (22.1%) 19 (6.4%) 79 (26.4%)
 >68.9 years 304 92 (30.3%) 22 (7.2%) 71 (23.4%)
Gender p = 0.263 p = 0.417 p = 0.013
 Male 347 97 (28%) 21 (6.1%) 73 (21%)
 Female 256 61 (23.8%) 20 (7.8%) 77 (30.1%)
 Tumour location p = 1.000 p = 0.280 p = 0.006
 Colon 438 115 (26.3%) 33 (7.5%) 122 (27.9%)
 Rectum 165 43 (26.1%) 8 (4.8%) 28 (17%)
Depth of invasion (pT) p < 0.001 p = 0.023 p < 0.001
 pT1 77 7 (9.1%) 0% 8 (10.4%)
 pT2 76 22 (28.9%) 5 (6.6%) 12 (15.8%)
 pT3 270 63 (23.3%) 16 (5.9%) 70 (25.9%)
 pT4a 122 42 (34.4%) 13 (10.7%) 37 (30.3%)
 pT4b 58 24 (41.4%) 7 (12.1%) 23 (39.7%)
Node involvement (pN) p = 0.679 p = 0.374 p = 0.172
 pN0 380 95 (25%) 26 (6.9%) 88 (23.2%)
 pN1 155 44 (28.4%) 8 (5.2%) 39 (25.2%)
 pN2 68 19 (27.9%) 7 (10.3%) 23 (33.8%)
Systemic metastasis (M) p < 0.001 p = 0.059 p = 0.101
 M0 563 137 (24.3%) 36 (6.4%) 136 (24.2%)
 M1a 33 15 (45.5%) 3 (9.1%) 10 (30.3%)
 M1b 7 6 (85.7%) 2 (28.1%) 4 (57.1%)
AJCC/UICC TNM Stage p < 0.001 p = 0.106 p = 0.008
 Stage I 130 27 (20.8%) 5 (3.8%) 18 (13.8%)
 Stage II 237 64 (27%) 21 (8.9%) 65 (27.4%)
 Stage III 196 46 (23.5%) 10 (5.1%) 53 (27%)
 Stage IV 40 21 (52.5%) 5 (12.5%) 14 (35%)
CEA serum levelb p = 0.017 p = 0.818 p = 0.005
 ≤5 ng/mL 303 75 (24.8%) 21 (6.9%) 69 (22.8%)
 >5 ng/mL 92 35 (38%) 7 (7.6%) 35 (38%)