Table 3.

Five-year overall and cancer-related survival rates according to the main clinicopathological characteristics, NLR, PLR and PC for the 603 patients under study.

	No. of patients	5-year survival rate
		Overall	Cancer-related
Age		p < 0.001	p = 0.022
≤68.9 years	299	85.9	89.4
>68.9 years	304	64.6	79.3
Gender		p = 0.055	p = 0.052
Male	347	73.7	82.6
Female	256	77.2	87.7
Tumour location		p = 0.699	p = 0.818
Colon	438	74.8	84.1
Rectum	165	76.1	86.4
Depth of invasion (pT)		p < 0.001	p < 0.001
pT1	77	89.9	100
pT2	76	86.5	90.9
pT3	270	80.8	90.8
pT4a	122	54.5	65.2
pT4b	58	55.2	61.5
Node involvement (pN)		p < 0.001	p < 0.001
pN0	380	81.6	92.5
pN1	155	71.1	78.6
pN2	68	44.7	46.9
Systemic metastasis (M)		p < 0.001	p < 0.001
M0	563	77.8	87.8
M1a	33	46.5	50.8
M1b	7	0	0
AJCC/UICC TNM Stage		p < 0.001	p < 0.001
Stage I	130	89.2	97
Stage II	237	79.1	91.6
Stage III	196	68	75.5
Stage IV	40	37.9	45.8
CEA serum levela		p < 0.001	p < 0.001
≤5 ng/mL	303	78.6	86.1
>5 ng/mL	92	58.3	73.2
Neutrophil-to-lymphocyte ratio		p < 0.001	p = 0.022
L-NLR	445	79.8	86.6
H-NLR	158	62.5	79.4
Platelet-to-lymphocyte ratio		p = 0.070	p = 0.239
L-PLR	562	75.9	86.6
H-PLR	41	65.9	79.4
Platelet count		p = 0.122	p = 0.151
L-PC	453	76.3	85.2
H-PC	150	71.8	83.5

^aCEA serum level was available for 401 patients.