Table IV.
Prevalence of factors associated with reproduction among LS women with EC compared with patients with sporadic EC.
| Factor | Total EC (n=160) | LS-associated EC (n=50) | Sporadic EC (n=110) | P-value |
|---|---|---|---|---|
| No. of pregnanciesa | 2.15 | 2.25 | 2.04 | 0.431b |
| No. of deliveriesa | 1.79 | 1.84 | 1.73 | 0.594b |
| Spontaneous abortions, n (%) | ||||
| 0 | 129 (80.6) | 45 (90.0) | 84 (76.4) | 0.043c |
| ≥1 | 31 (19.4) | 5 (10.0) | 26 (23.6) | |
| Induced abortions, n (%) | ||||
| 0 | 140 (87.5) | 47 (94.0) | 93 (84.5) | 0.094c |
| ≥1 | 20 (12.5) | 3 (6.0) | 17 (15.5) | |
| Age at menarchea | 13.6 | 13.4 | 13.7 | 0.375b |
| Age at menopausea | 50.4 | 50.3d | 50.5e | 0.878b |
| Duration of HRT use, yearsa,f | – | 11.3 | 9.7 | 0.407b |
| Duration of hormonal contraception | – | 6.6 | 6.9 | 0.83 |
| use, yearsa |
a
The mean values are indicated.
b
According to the Student's t-test.
c
According to the Pearson Chi-square test.
d
n=21
e
n=69.
f
Regarding ever users of HRT, n=25 LS patients and n=61 sporadic EC patients. EC, endometrial cancer; LS, Lynch syndrome; HRT, hormone replacement therapy.