Table I.
Associations between clinicopathological characteristics and LNR/LODDS (n=192).
| LNR, n (%) | LODDS, n (%) | |||||||
|---|---|---|---|---|---|---|---|---|
| Characteristics | LNR1(n=124) | LNR2(n=33) | LNR3(n=35) | P-value | LODDS1(n=120) | LODDS2(n=17) | LODDS3(n=55) | P-value |
| Gender | 0.400 | 0.695 | ||||||
| Male | 75 (61) | 16 (49) | 22 (63) | 72 (60) | 11 (65) | 30 (55) | ||
| Female | 49 (39) | 17 (51) | 13 (37) | 48 (40) | 6 (35) | 25 (45) | ||
| Age (years) | 0.429 | 0.041 | ||||||
| <60 | 72 (58) | 18 (55) | 16 (46) | 71 (59) | 12 (71) | 23 (42) | ||
| ≥60 | 52 (42) | 15 (45) | 19 (54) | 49 (41) | 5 (29) | 32 (58) | ||
| Location | 0.071 | 0.399 | ||||||
| Left colon | 12 (10) | 9 (27) | 5 (14) | 13 (11) | 2 (12) | 11 (20) | ||
| Right colon | 33 (26) | 5 (15) | 5 (14) | 31 (26) | 3 (17) | 9 (16) | ||
| Rectum | 79 (64) | 19 (58) | 25 (72) | 76 (63) | 12 (71) | 35 (64) | ||
| Max (cm) | 0.905 | 0.366 | ||||||
| <5 | 94 (76) | 26 (79) | 26 (74) | 88 (73) | 15 (88) | 43 (78) | ||
| ≥5 | 30 (24) | 7 (21) | 9 (26) | 32 (27) | 2 (12) | 12 (22) | ||
| Differentiation | 0.059 | 0.141 | ||||||
| High | 35 (28) | 6 (18) | 5 (14) | 33 (27) | 4 (23) | 9 (16) | ||
| Moderate | 75 (61) | 19 (58) | 20 (57) | 72 (60) | 11 (65) | 31 (57) | ||
| Poor | 14 (11) | 8 (24) | 10 (29) | 15 (13) | 2 (12) | 15 (27) | ||
| T stage | 0.075 | 0.152 | ||||||
| T1 | 3 (2) | 0 (0) | 0 (0) | 2 (2) | 0 (0) | 1 (2) | ||
| T2 | 40 (32) | 5 (15) | 7 (20) | 4 (33) | 2 (12) | 10 (18) | ||
| T3 | 44 (36) | 9 (27) | 16 (46) | 43 (36) | 6 (35) | 20 (36) | ||
| T4 | 37 (30) | 19 (58) | 12 (34) | 35 (29) | 9 (53) | 24 (44) | ||
| pN | <0.001 | <0.001 | ||||||
| N0 | 108 (87) | 0 (0) | 0 (0) | 100 (83) | 4 (24) | 4 (7) | ||
| N1 | 16 (13) | 29 (88) | 23 (66) | 20 (17) | 13 (76) | 35 (64) | ||
| N2 | 0 (0) | 4 (12) | 12 (34) | 0 (0) | 0 (0) | 16 (29) | ||
| Nodes retrieved | 0.784 | 0.071 | ||||||
| <12 | 79 (64) | 20 (61) | 24 (69) | 70 (58) | 14 (82) | 39 (71) | ||
| ≥12 | 45 (36) | 13 (39) | 11 (31) | 50 (42) | 3 (18) | 16 (29) | ||
| CEAa (ng/ml) | 0.038 | 0.024 | ||||||
| <5 | 80 (74) | 18 (60) | 13 (50) | 77 (75) | 10 (67) | 24 (52) | ||
| ≥5 | 28 (26) | 12 (40) | 13 (50) | 26 (25) | 5 (33) | 22 (48) | ||
a
Some values were missing for this variable. LNR, lymph node ratio; LODDS, log odds of positive lymph nodes; Max, maximum tumor size; pN, positive nodes; CEA, preoperative serum carcinoembryonic antigen.