Table II.
Association between the relative expression of miR-638 and the clinicopathological characteristics of patients with hepatocellular carcinoma.
| miR-638 expression | ||||
|---|---|---|---|---|
| Clinicopathological characteristics | No. of cases (n=60) | High (19) | Low (41) | P-value |
| Age, years | 0.781 | |||
| <50 | 26 | 9 | 17 | |
| ≥50 | 34 | 10 | 24 | |
| Gender | 0.089 | |||
| Female | 13 | 7 | 6 | |
| Male | 47 | 12 | 35 | |
| HBV infection status | 0.114 | |||
| + | 44 | 11 | 33 | |
| − | 16 | 8 | 8 | |
| Tumor size, cm | 0.774 | |||
| ≤5 | 22 | 6 | 16 | |
| >5 | 38 | 13 | 25 | |
| AFP level, µg/l | 0.042 | |||
| ≤20 | 20 | 10 | 10 | |
| >20 | 40 | 9 | 31 | |
| TNM stage | 0.146 | |||
| I+II | 20 | 9 | 11 | |
| III+IV | 40 | 10 | 30 | |
| Portal vein invasion status | 0.025 | |||
| Yes | 22 | 3 | 19 | |
| No | 38 | 16 | 22 | |
| Distant organ hepatic metastasis status | 0.083 | |||
| Yes | 19 | 3 | 16 | |
| No | 41 | 16 | 27 | |
miR, microRNA; HBV, hepatitis B virus; TNM, tumor node metastasis; AFP, α-fetoprotein.