Fig. 10. (A) Structure of theranostic probe TPETP–AA–Rho–cRGD and schematic representation of the proposed singlet oxygen self-reporting mechanism. (B and C) CLSM images of the probe (10 μM), incubated MDA-MB-231 cells, with light irradiation at a power density of 0.10 W cm^–2 for (B1 and C1) 0 min, (B2 and C2) 2 min, (B3 and C3) 4 min and (B4 and C4) 4 min in the presence of Asc (100 μM). (B1–B4) Red fluorescence (TPETP, E _x: 405 nm; E _m: > 650 nm); (C1–C4) green fluorescence (Rho, E _x: 488 nm, E _m: 505–525 nm). Reprinted with permission from ref. 51. Copyright 2015 Royal Society of Chemistry.