Fig. 11. (A) The molecular structure of the targeted theranostic platinum(iv) prodrug TPS–DEVD–Pt–cRGD. (B) Schematic illustration of the targeted theranostic platinum(iv) prodrug TPS–DEVD–Pt–cRGD with a built-in AIE light-up apoptosis sensor for non-invasive in situ early evaluation of its therapeutic responses. (C) Real-time CLSM images displaying the apoptotic progress of TPS–DEVD–Pt–cRGD (5 μM) stained U87-MG cells. The green fluorescence is from TPS (E _x: 488 nm, E _m: 505–525 nm). Reprinted with permission from ref. 54. Copyright 2014 American Chemical Society.