Representative IHC staining for E-cadherin and vimentin. IHC analysis for E-cadherin demonstrated (A) negative staining in the pleomorphic carcinoma subtype of PSC and (B) strongly positive membranous staining in PA. Conversely, IHC staining for vimentin was (C) strongly positive in the cytoplasm in the pleomorphic carcinoma subtype of PSC and (D) negative in PA. Magnification, ×400. IHC, immunohistochemical; PSC, pulmonary sarcomatoid carcinoma; PA, pulmonary adenocarcinoma.