Figure 4.

PCBLs, OPAs and PPAs induce intrinsic apoptosis in ovarian cancer cells. Results are representative of ≥2 independent experiments that exhibited similar patterns. Protein expression levels were measured by densitometry and the values above and below the blots indicate the relative ratios. PCBL, Chinese bayberry leaf prodelphinidin extract; OPA, oligomeric proanthocyanidin; PPA, polymeric proanthocyanidin. Puma, p53-upregulated modulator of apoptosis; Bcl-2, B-cell lymphoma-2; Bcl-xL, Bcl-extra large; Bax, Bcl-2-associated X protein; Bad, Bcl-2-associated death promoter.