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. 2017 Mar 17;13(5):3817–3822. doi: 10.3892/ol.2017.5868

Figure 3.

Figure 3.

Cell cycle gene expression upon Rnf2 knockdown. mRNA expression levels of (A) p14-ARF and (B) p16-InK4ado not show significant differences between Rnf2 silenced GC cells and control cells. mRNA expression levels of (C) p21 and (D) p27 are significantly elevated in Rnf2 silenced GC cells compared with control cells. *P<0.05. Bars represent the mean, and error bars represent the standard deviation. Rnf2, ring finger protein 2; p14-ARF, alternative reading frame protein 14; GC, gastric cancer; p16-InK4a, protein 16-cyclin dependent kinase inhibitor 2A; KD, knockdown.