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. 2017 Mar 17;2:16045. doi: 10.1038/sigtrans.2016.45

Figure 7.

Figure 7

FGF-2-expressing bladder carcinomas express high levels of CTLA-4, PD-1 and PD-L1 and harbor fewer mutations and copy number gene variations. (a, b) Heat maps and correlation coefficients between the expression of FGF-2 and CTLA-4, PDCD1 (PD-1) and CD274 (PD-L1). (c, d) Invasive bladder carcinomas expressing high levels of FGF-2 harbor fewer mutations and copy number variations than invasive bladder carcinomas expressing low levels of FGF-2. FGF-2, fibroblast growth factor 2; TCGA, the cancer genome atlas.