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. 2017 May 12;7:1872. doi: 10.1038/s41598-017-02052-0

Table 1.

Genome scan for milk production traits in a daughter design of 1,941 dairy goats, based on haplotype-based linkage analyses.

CH I Trait Breed Significance level LRT Position (Mb) 95% –CI (min max) Substitution effect Candidate genes
1 PC Alpine *** 41.6 1.382 1.362–1.449 0.36 PDE9A
1 PC All ** 51.8 1.418 1.404–1.434 0.30
2 FY All ** 51.8 0.239 0.237–0.241 0.33
5 PC Saanen ** 31.5 0.205 0.196–0.224 0.32
6 FC All *** 66.2 0.764 0.743–0.812 0.32
6 FC Saanen *** 44.3 0.805 0.746–0.872 0.44 Caseins cluster
6 PC Alpine *** 62.5 0.814 0.786–0.848 0.37 Caseins cluster
6 PC All *** 161.3 0.824 0.792–0.842 0.50 Caseins cluster
6 PC Saanen *** 99.6 0.824 0.791–0.845 0.66 Caseins cluster
7 FC Alpine ** 36.8 0.037 0.013–0.042 0.30 SLC27A1
11 PC Alpine ** 39.9 0.900 0.887–0.906 0.35 PAEP
14 FY Alpine *** 39.9 0.034 0.025–0.046 0.30
14 FY All ** 53.8 0.037 0.025–0.048 0.28
14 FC All *** 126.2 0.111 0.092–0.124 0.48 DGAT1
14 FC Saanen *** 60.8 0.123 0.092–0.143 0.50
14 FC Alpine *** 70.8 0.155 0.146–0.160 0.42
19 PY All ** 52.3 0.285 0.248–0.290 0.27 PLD2 GGT6 ALOX12, ALOX 12B, ALOX 15
21 FC All ** 52.0 0.554 0.526–0.576 0.27
21 FC Alpine ** 37.2 0.571 0.538–0.588 0.27
21 PC All ** 49.9 0.578 0.570–0.585 0.27
21 PY All *** 58.0 0.634 0.627–0.640 0.31
21 MY All ** 53.2 0.635 0.627–0.642 0.29
25 FC Saanen ** 32.4 0.101 0.099–0.103 0.35
28 PC Alpine ** 33.7 0.322 0.295–0.361 0.31

Significance level: ***: 5% genome-wide; ** 1% chromosome-wide. The 95% confidence intervals of the QTL locations were estimated by logarithm of odds drop-off.