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Comparison of the binding conformation of in situ click chemistry reaction hit compounds with crystalized SC558. a In COX-2 isozyme (PDB:6COX) the compound 18 (cyan carbon) and SC558 (green carbon) are displayed in stick mode and surface of compound 18 is highlighted (grey) color; b compound 21 (magenta carbon) and SC558 (green carbon) are displayed in stick mode and surface of compound 21 is highlighted (grey) color
