Table 1.
Human and murine pancreatic stellate cell lines utilized in vitro. Details, including cell type, species of origin, immortalization status, and disease of origin, are provided for each cell line (PDAC indicates pancreatic ductal adenocarcinoma, GEMM indicates genetically engineered mouse model).
| # | Name | Cell Type | Species | Immortalization Status | Disease of origin/Genotype |
|---|---|---|---|---|---|
| 1 | HPF | fetal pancreatic fibroblast | human | non-immortalized | Normal |
| 2 | PaSC | PSC | mouse | immortalized | Normal |
| 3 | m-PSC-PDAC-1 | PSC | mouse | non-immortalized | PDAC GEMM: Mist1(KRAS G12D/+) |
| 4 | m-PSC-PDAC-2 | PSC | mouse | non-immortalized | PDAC GEMM: Mist1(KRAS G12D/+) |
| 5 | m-PSC-PDAC-3 | PSC | mouse | non-immortalized | PDAC GEMM: (Brca1 flox2/flox2; Kras LSL-G12D/+; p53 LSL-R27OH/+; Pdx1-cre) |
| 6 | h-PSC-PDAC-1 | PSC | human | non-immortalized | PDAC |
| 7 | h-PSC-PDAC-2 | PSC | human | non-immortalized | PDAC |
| 8 | h-iPSC-PDAC-1 | PSC | human | immortalized | PDAC |
| 9 | h-PSC-CP-1 | PSC | human | non-immortalized | chronic pancreatitis |
| 10 | RLT-PSC | PSC | human | immortalized | chronic pancreatitis |