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. 2017 May 11;7:1750. doi: 10.1038/s41598-017-01947-2

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Dependence of the difference in current before and after the addition of H₂O₂ on log[miRNA] on a gold slide electrode following hybridisation with probe miRNA that is labelled with PtNPs. The applied potential is −0.25 V in 1 mM DPBS. Δi represents the difference in current before and after addition of 20 µM H₂O₂. Error bars are from an n = 3 study and range from 4–13%. The calibration plot is fit with a 4 parameter logistic function (blue line).